Claudia Simona Cambrea 1, S. Rugină 1, Margareta Ilie 2, Claudia Nina Rugină 3, Valeria Stroia 4, I. Sora 4, O. Carp 5, R. Baz 6
1 Universitatea „Ovidius” Constanţa, Facultatea de Medicină, Clinica de Boli Infecţioase
2 Clinica de Boli Infecţioase copii, Spitalul Clinic de Boli Infecţioase Constanţa
3 Laborator Clinic, Spitalul Clinic de Boli Infecţioase Constanţa
4 Universitatea „Ovidius” Constanţa, Facultatea de Medicină, Clinica de Pediatrie
5 Secţia de neurochirurgie, Spitalul Clinic Judeţean de Urgenţă Constanţa
6 Universitatea „Ovidius” Constanţa, Facultatea de Medicină, Clinica de Imagistică medicală
Abstract
Sepsis with candida albicans to infant – Case presentation. Introduction: Fungal infections in neonates and infants are associated with the aggressive use of chemotherapy, widespread use of broad spectrum antibiotics, extensive use of indwelling intravascular catheters, the immunodeficiency associated with AIDS and neonates intensive care units. Disseminated candidiasis and candidemia have become a frequent problem in neonatal intensive care units. Objective: To present a case of sepsis with Candida albicans in an infant of 6 months old with multiple hospitalizations, with prolonged antibiotic therapy and indwelling intravascular catheter. Results: We present a case of a female infant who was hospitalized for a Bacterial meningo-encephalitis during January 2007 in pediatric intensive care unit of County Clinical Hospital of Constanta. In this unit patient received complex etiologic treatment and specific treatment. After this episode the child was transferred in Children Infectious Diseases Department with Diagnosis of TB meningo-encephalitis. During both hospitalizations infant received broad spectrum antibiotics, tuberculostatic drugs, indwelling intravascular catheter, naso-gastric probe and a neurosurgical intervention in order to drain internal hydrocephaly secondary to bacterial meningo-encephalitis. After 3 months of hospitalization the child presents an episode of sepsis with Candida albicans that required treatment with Fluconazole for 2 weeks. Conclusions: In this case sepsis with Candida albicans in an infant is a disease associated with medical invasive procedures and broad spectrum antibiotics for a long period of time.