D. Orășeanu *, C. Ulmeanu *, Dana Păcurar *, L. Miclea **, E. Ciofu *
* Conf. Dr. Dumitru Orășeanu, Conf. Dr. Coriolan Ulmeanu, Dr. Dana Păcurar, Prof. Dr. Eugen Ciofu – U.M.F. “Carol Davila” București, Catedra de Pediatrie, Spitalul Clinic Central de Copii
** Dr. Liviu Miclea – U.M.F. “Carol Davila” București, Catedra de Toxicologie
Article information. Therapeutical Practice · Ther Pharmacol Clin Toxicol 1997;1(2):69–74 · Article in Romanian with an English abstract
Abstract
In mushroom poisonings, when mushroom identification is not possible, diagnosis and prognosis are based on the delay of onset of gastrointestinal disturbance. Intoxications with a short latent period are usually harmless. When the latent period exceeds six hours amatoxin mushrooms are mostly involved and prognosis depends on the severity of the hepatitis. Currently no specific antidote of amatoxin is available. Treatment includes early supportive measures, amatoxins elimination by renal (early forced diuresis) and gastrointestinal (diarrhea, oral activated charcoal) routes. Penicilin G an silymarine may have some antitoxic effect.
Keywords: mushroom; poisoning; amanitins
Cite as: Orășeanu D, Ulmeanu C, Păcurar D, Miclea L, Ciofu E. Intoxicațiile acute cu ciuperci. Aspecte clinico-terapeutice. Ther Pharmacol Clin Toxicol. 1997;1(2):69–74.