FARMACOTERAPIA DURERII NEUROPATICE – ASPECTE ACTUALE

July 1, 2001

O. C. Mungiu*, Irina-Maria Jaba*, Georgeta Dunărea Ionescu*
*Prof. dr. Ostin C. Mungiu, Prep. drd Irina-Maria Jaba, dr. biol. Georgeta Dunărea Ionescu – Catedra de Farmacologie – Toxicologie ­ Algtziologie, Facultatea de Medicină, UMF “Gr. T. Popa”, Iași

Abstract

The pharmacotherapy of the neuropathic pain – updates
Neuropathic pain is determined by nervous lesions. This implies either peripheral and central pathophysiological phenomena. Numerous treatment modalities are available and include systemic medication, physical modalities, psychological modalities, invasive procedures (sympathetic blocks, epidural steroids), spinal cord stimulators, intrathecal morphine pump and various surgical techniques. Most neuropathic pain respond poorly to NSAIDS and opioid analgesics. The mainstay of treatment are the co­ analgesics – antidepressants, anticonvulsants, systemic local anesthetics.