Madelena I. Drăgan *, Ana Maria Tudor **, Gh. Jugulete ***
* Profesor universitar dr. Madelena I. Drăgan, UMF “Carol Davila”, Institutul de Boli Infecțioase “Prof. Dr. Matei Balș”, Clinica de Boli Infecțioase III – Pediatrie
** Asistent universitar dr. Ana Maria Tudor, UMF “Carol Davila”, Institutul de Boli Infecțioase “Prof. Dr. Matei Balș”, Clinica de Boli Infecțioase III – Pediatrie
*** Preparator universitar dr. Gheorghiță Jugulete, UMF “Carol Davila”, Institutul de Boli Infecțioase “Prof. Dr. Matei Balș”, Clinica de Boli Infecțioase III – Pediatrie
Abstract
Using protease inhibitors as potent antiretroviral agents increased the efficacy of treatment in HIV/AIDS patients. Therefore, we had studied the efficacy of nelfinavir in HIV infected children, in a retrospective study. This antiretroviral agent had a good virologic and immunologic response, as it is pointed in our study. The same results were obtained in other published studies. Nelfinaviris a potent protease inhibitor and can be used as initial and alternative therapy in HIV infected children.