EFECTE SECUNDARE GASTROINTESTINALE ALE ANTIBIOTICELOR

April 1, 1995

Victoria Aramă*, S. Aramă**
* Dr. VICTORIA ARAMĂ – asistent., Clinica I Boli Infecțioase Colentina, UMF “Carol Davila”, București
** Dr. Sorin ARAMĂ – asistent., Catedra de Fizioparologie, UMF “Carol Davila”, București

Abstract

Gastro-intestinal disorders are the most frequent side effects of antibiotic therapy. In this article they are classified as follows: a) pseudomembranos colitis-less frequent but very serious; ocurring due to lincosamids or broad spectrum betalactamines, by intestinal proliferation of toxic-producing Clostridium difficile. b) minor diarrhoreas; c) dyspeptic syndrome much more frequent but less serious, ocurring after any antibiotic which may after the normal enteric flora or may disturb the motor or secretory gastro-intestinal functions. The most recent progress in physiopathology, diagnosis and treatment of pseudomembranes colitis are pointed up.

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