CORELAȚIA DINTRE INFECȚIA CU HELICOBACTER PYLORI (HP) ȘI LEZIUNILE MUCOASEI GASTRO-DUODENALE, PRODUSE DE A.I.N.S. (Studiu endoscopic și testul rapid la urează)

June 1, 1999

Mihaela Albu *, A. Lenghel **, V. Porumb **, Corina Popa **, O. Frățilă **, B. Cuparencu ***
* Dr. Mihaela Albu – asistent universitar semiologie medicală, medic rezident medicină internă, anul V, doctorand, Spital Clinic județean, Clinica Medicală I, Oradea
** Conf. Dr. A. Lenghel – Spital Clinic județean, Clinica Medicală IV, Oradea
** Șef lucrări Dr. V. Porumb, Spital Clinic județean, Clinica G-E, Oradea
** Șef lucrări Dr. Corina Popa, Spital Clinic Județean, Clinica G-E, Oradea
** Dr. O. Frățilă – asistent universitar medicină internă, medic rezident medicină internă anul V, doctorand, Spital Clinic județean, Clinica Medicală IV, Oradea
*** Prof. Univ. Dr. Doc. B. Cuparencu, Catedra de Farmacologie, Facultatea de Medicină – Oradea

Abstract

A number of 44 patients were endoscopically examined, they presenting subjectif and objectif accuses on the gastro­ duodenal tract, as a result of some NSAIDs administration (acetilsalicilic acid, diclofenac, pyroxicam, phenilbutazone, indomethacine). At the same time, the patients were tested to emphasize the presence of Helicobacter pylori (HP) by the flash test at urease. It was ascertained that HP is not present at all the patients, but only at 69%. More, at the pylor level, where HP is frequent, no endoscopic lesions were ascertained. One can draw the conclusion that HP doesn’t condition the appearance of gastro-duodenal lesions caused by NSAIDs.