M. Nechifor*
Conf. dr. Mihai Nechifor, Disciplina de Farmacologie, Universitatea de Medicină și Farmacie “Gr.T.Popa”, Iași
Abstract
The competitive antagonists of PAF at receptors’ level will become one of the treatments for gastric and duodenal ulcers endoxinic shock, asthma, acute inflammation, acute miocardic infarct, thromboembolic disease, etc. Two main series of competitive antagonists of PAF were intensively studied: • substances of vegetable origin: terpenoids (ginkgolides), lignans and neolignans (kadsurenone and buserane, etc.), gliotoxines; • synthetic and semisyinthetic antagonists lipidic analog (CV 3988) and nonlipidic antagonists (hetrazepines).