CERCETĂRI EXPERIMENTALE PRIVIND INFLUENȚAREA PRIN BUTANDIOL A CAPACITĂȚII DE EXPLORARE A ANIMALELOR SUPUSE UNEI ISCHEMII CEREBRALE

December 1, 1999

Isabel Cristescu *, B. Voiculescu **, L. Podoleanu **
* Dr. Isabel Cristescu – asistent universitar, Catedra de farmacologie UMF Carol Davila, București
** Dr. Bogdan Voiculescu – șef lucrări, Catedra de anatomie UMF București; Dr. Lucian Podoleanu – șef lucrări, Catedra de anatomie UMF Bucureșli

Abstract

In this study we investigated the influence of butandiol of the exploring capacity of the animals undergoing cerebral ischaemia, the positive effect of butandiol being due to the preferential use of ketonic bodies as a source of energy, which limits anaerobic glycolysis and thus diminishes lactate production. We notice a tendency to diminishing post-ischaemic hypermotility, also the efficiency of this product in the amelioration on the disturbances of the exploring capacity of the ischaemiated animals.