Elena Copaciu *
* Dr. Elena Copaciu – Medic primar ATI, şef de secţie; şef de lucrări UMF Carol Davila, Clinica ATI, Spitalul Universitar de Urgenţă, Bucureşti
Abstract
ln the last years was consisted a growing of fungical infections incidence to the critical patient from ICU units, but also the increasing of resistances to the antifungical treatment an. The most frequently factors of risk are the opportunist stipes and in appearance of resistances are involved the cellular and molecular mechanism and fungical biofilms which appear to the patient with implantable medical device. lt was necessary to elaborate a new therapeutic strategy, opening with enhance the doses, combined antifungical therapy, immunomodulated therapy, the new molecule design and the germs research from biofilms.