Carmen Avramescu 1, Maria Bălășoiu 1, Adriana Turculeanu 1, Anca Ungureanu 1, Isabela Siloși 1, Simona Neamțu 2, Oana Ionete 1, Mădălina Sibișeanu 3
1 Disciplina Microbiologie – Imunologie, UMF Craiova
2 Disciplina Hematologie – Imunologie, UMF Craiova
3 Laborator – Medic rezident, Spitalul Clinic de Urgență Craiova
Abstract
Premises: The antibiogram is one of the most frequent determination from a bacteriology laboratory being required on multiple clinical, epidemiological and research considerations. Scientifically, antibiogram is made for the research of the resistance phenomenon through which the bacterias with etiological role in human infections are or become resistant to antibiotics. Objectives: The object of the study is to estimate the resistance of the several pathogenic germs (Klebsiella, Escherichia coli, Proteus, Staphylococcus aureus) isolated from various pathological products, to several betalactamic antibiotics usually used in medical practice: Imipenem+Cilastatin, Ampicillin + Sulbactam, Ampicillin + Acid clavulanic, Cefotaxim, Ceftazidim, Ampicillin. Material and method: In our study, there were used bacterian cultures isolated from pathological products from a lot of 37 adult patients, most of them with urogenital pathology and acute or chronic respiratory infec tions affections. The sensibility and resistance of the pathogenical germs reminded before using difusimetrical antibiogram. Results and conclusions: E. coli became resistant to Imipenem+Cilastatin, the sensibility of Klebsiella and Proteus was not modified, while the sensibility of the Staphylococcus dropped, although the Staphylococcus remained receptive to this antibiotic. E.coli kept it’s sensibility towards Ampicillin+Acid clavulanic action unlike the other studied germs where a tendency to became resistant was observed. The Ampicillin+Sulbactam only E. coli and Proteus have an intermediate sensibility. The Staphylococcus is the one who responds best to Cefotaxim therapy, followed by Proteus . In the case of Klebsiella, one can, one can see the tendency to become resistant to this antibiotic, while in the case of the E. coli the definitive resistance to Cefotaxim is observed. None of the germs are sensible anymore to Ceftazidim. Towards Ampicillin it is observed the tendency to become resistant, only the Staphylococcus and Proteus have an intermediate sensibility.