INTERACŢIUNI FARMACOCINETICE ŞI IMUNOLOGICE ALE SISTEMELOR TERAPEUTICE LIPOZOMALE

March 1, 2008

A. Neamţu 1, C. Neamţu 2, O. C. Mungiu 3
1 Asist. drd. – Disciplina de Biofizică şi Bioinstrumentaţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Gr. T. Popa”, Iaşi
2 Prof. Dr. – Disciplina de Fiziologie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Gr. T. Popa”, Iaşi
3 Prof. Dr. – Disciplina de Farmacologie, Toxicologie şi Algeziologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie „Gr. T. Popa”, Iaşi

Abstract

Liposomes are largely used in fundamental medical research and especially in physio-pharmacological one. They are often used as transporters for different types of substances including drugs. That is why a comprehensive understanding of their interaction within the body is extremely important. There is a great amount of experimental data in this respect in the field literature, few even contradictory. Because of this great diversity of data there is need for some systematization which will be useful in understanding the liposome biological interactions. This material tries succinctly to present such a synthetic view, which, because of the huge amount of data published in the last 20 years, will surely be subjected to refinements.