Manuela Podani *, Olga Dorobăț **, Elena Mitache *, Marina Pană ***
* Dr. Manuela Podani, medic primar; Dr. Elena Mitache, șef laborator – Institutul de Boli Infecțioase “Prof. Dr. M. Balș”, București
** Dr. Olga Dorobăț, șef laborator – Spitalul de Boli infecțioase Dr. Victor Babeș, București
*** Dr. Marina Pană – Institutul Cantacuzino, Centrul de Referință pentru Streptococi
Abstract
Penicillin resistence in pneumococci, often associated to resistence to other antibiotics, represents nowadays an important problem of Public Health. Our study, conducted over a 5 year’s period aimed resistence the establishement of the pattern of invasive pneumococci, isolated in Bucharest. The results showed a high level of penicillin resistence: 30,4% by diffusimetric method. We compared our results with the data from the Center of Reference for Streptococci, concerning the resistence in the early 90’. We noted the evolution trends of the resistence concerning the clinically most used antibiotics and commented their therapeutic implication.