Carmen Manciuc 1, Cristina Nicolau 1, A. Vâţă 2, L.J. Prisăcaru 1, Diana Matei 3, Adina Boghian 3, Alexandra Largu 4, Carmen Dorobăţ 1
1 Iaşi HIV-AIDS Regional Center
2 The University of Medicine and Pharmacy “Gr. T. Popa” of Iaşi
3 The “Sfânta Parascheva” Infectious Diseases Hospital of Iaşi
4 Psychology masters
Abstract
Introduction. The aim of the study was to mark the nature of HIV transmission to the newborns from the seropositive mothers in the NE area of Romania, monitored by The Regional Center for HIVAIDS in Iaşi. Method. 92 HIV-positive pregnant women and their newborn babies were retrospectively analyzed and monitored between January 2005 – March 2010. Results: The incidence of the pregnant HIV- positive patients was 1.47/month in a female population of 638 seropositive-patients; the median age was 20.4 years; 72.1% were from suburban areas and 94.6% were HIV positive antepregnancy, 52.2% were with AIDS (72.8% with ARV treatment). In 22.5% of all cases, the ARV treatment was modified; the median CD4 count was 356/mmc (56-702/mmc), VL – 10700/ml. The prophylaxis of HIV transmission was performed for all of the children, six of whom were seropositive with a significant VL. Conclusions. Mother to child transmission could be avoided through a correct ARV therapy and prophylaxis of the newborn according to a working team comprised of an infectious diseases specialist, a neonatologist, a gynecologist, a social worker and a psychologist.