Em. Manolescu *, Camelia Vreto **
* Prof. dr. Emanoil Manolescu, Catedra de Farmacologie, UMF Carol Davila, București
** Dr. Camelia Vreto, medic primar pediatrie – Constanța
Abstract
Claritromicine is a new macrolide, presenting advantages compared to erythromicine in terms of pharmacokinetics, broad antibacterial spectrum and reduced secundary effects. Therefore it has a rapid, complete digestive absorbtion uninfluenced by food, prolonged active plasma levels and greater tissular than plasma concentrations. The antibacterial spectrum is broader and it is especially active in respiratory and ENT infections with Legionella, Chlamydia and Mycobacterium avium. The secondary effects are uncommon and without clinical relevance.