Motoi O., Ditoiu A. V., Andronesi A., Ismail G., Voiculescu M.
Fundeni Clinical Institute, Internal Medicine and Nephrology Center, Bucharest
Abstract
Hepatic osteodistrophy, one of the consequences of the continuous deterioration of liver function and chronic cholestasis, represents an important morbidity factor for patients waiting for liver transplant. Bone mineral density continues to decrease after transplant explaing the high incidence of fractures. Pretransplant osteodistrophy screening is mandatory and prophylaxis and treatment should be started as soon as possible to prevent further deterioration of BMD after transplant. Due to the specific problems encountered in liver cirrhosis, therapeutic alternatives must be carefully selected with a special regard to risk-benefit ratio.