M. Angelescu *, C. Alexandru **
* Prof. Dr. Mircea Angelescu, Clinica de boli infecțioase “Colentina”, U.M.F “Carol Davita” București
* Dr. Călin Alexandru, Secția de Chirurgie plastică și reparatorie a Spitalului Clinic Universitar, București
Abstract
In serious burns – due to the extend of the affected surface or depth of lesions infection occurs in 95% of cases. Initially the infection may be due to soil-bacteria (Clostridium tetani, Cl. perfringens) or to the conditioned pathogenic flora of the skin (especially staphylococcus spp) in which case the synergic bactericid association – oxacillin – gentamicin is indicated. Subsequently the infection may be due to the nosociomial flora; methicillinoresitant staphylococci, enterococci, enterobacteriacee, Pseudomonas. In this cases, after bacterial isolation and “in vitro” antibiotic susceptibility test reserve antibiotics as vancomycin, parenteral cephalosporins, antipyocianic penicillins, each associated with an aminoglycozide or systemic fluoroquinolone. Antibiotic therapy will be clinically, paraclinically and bacteriologically monitorized.