SEVERE NEUROLOGICAL IMPAIRMENT AS INITIALMANIFESTATION OF HIV INFECTION – CLINICAL CASES

A. Vâţă ¹, Carmen Manciuc ¹, Cristina Nicolau ², L. Prisăcariu ², Gabriela Jugănariu ¹, Gh. Dorobăţ ¹, D. Duiculescu ³, Carmen Dorobăţ ^1
1 University of Medicine and Pharmacy “Gr T. Popa”
² Infectious Diseases Hospital Iasi
³ Infectious and Tropical Diseases Hospital “Dr. Victor Babes” Bucharest

Abstract

The neuro-cognitive impairment in HIV infected patients may take an extremely wide range of clinical manifestations and can occur early (acute retroviral syndrome) or late in the history of the infection We present three case reports of patients in whom some complex and atypical neurological manifestations led to the diagnosis of HIV infection after close colaboration of neurologists and infectious diseases specialists from several counties; the outcome and therapeutic approach are discussed. This kind of manifestations could become more frequent now in the newly diagnosed, late presenter, slow progressor patient.