Codrina Bejan 1, Carmen Manciuc 1, G. Dorobăţ 1, Laura Ghibu Carmen Dorobăţ 1
1 The University of Medicine and Pharmacy, Iaşi
Abstract
There is no standard definition of meningitis occurring post neurosurgical intervention. The diagnosis of the disease is difficult because of the high-frequency meningeal reactions in the context of preexisting symptoms that mask the signs and symptoms of meningitis. Cerebrospinal fluid examination is the standard for diagnosis. Material and methods Clinical and laboratory data were studied, as well as pre and post-antibiotherapy developments of case report forms of 68 patients with post- operative meningitis, hospitalized in the Clinic of Infectious Diseases, Iaşi, between 2004-2008. Objective. We designed a retrospective evaluation of patients with post-operative meningitis in terms of CSF parameters, etiologic spectrum, inflammatory syndrome, clinical signs and symptoms, fever span, duration of hospitalization. The statistics (“T student” test and Confidence Interval) supported the evolution of the patients under study. Conclusions. 1. The etiologic agent most frequently involved was Staphylococcus meti-R, consistent with field literature. 2. The first line therapeutic option, according to the our service’s experience, in line with the arguments of the present study: third-generation cephalosporins + fluoroquinolones / carbapenems + fluoroquinolones. Keywords: post-operative meningitis, cerebrospinal fluid, etiologic agent.