PARTICULAR DIAGNOSIS AND TREATMENT FEATURES OF ACASE OF COMMON VARIABLE IMMUNOGLOBULIN DEFICIENCYASSOCIATED WITH GLUTEN INTOLERANCE AND SEVEREMALABSORPTION SYNDROME

Georgescu A. ¹, Georgescu D. ², Dorobanţu D. ^3
1 Infectious Diseases Clinic, University of Medicine and Pharmacy Tirgu-Mures
² Gastroenterology Department, University of Medicine and Pharmacy Tirgu-Mures
³ Department of Plastic and Reconstructive Surgery, Emergency County Hospital Mures

Abstract

The authors present the case of a Common variable immunoglobulin deficiency (CVID) patient who has hypogammaglobulinemia, bowel involvement and severe malabsorption syndrome. Various problems related to positive and differential diagnosis are discussed within the framework of a very severe progression due to malabsorption syndrome with cachexia, numerous intercurrent pulmonary, intestinal, genital and skin infections and thrombophilia secondary to malabsorption. Eventually the course of disease is favourable partially thanks to the multidisciplinary approach undertaken.