Rozina Iagăru 1, Monica Luminos 1,2, Dorina Duma 3, Alina Cibea 4, Gh. Jugulete 1,5, Elena Gheorghe 6, Violeta Marinescu 6
1 Senior Infectious Disease Physician, Division Head, INBI “Prof. Dr. Matei Balş”, Bucharest
2 Associate Professor, “Carol Davila” University of Medicine and Pharmacy
3 Infectious Diseases Physician, Division Head, INBI “Prof. Dr. Matei Balş”, Bucharest
4 Pediatrics Resident, INBI “Prof. Dr. Matei Balş”, Bucharest
5 Assistant Professor, “Carol Davila” University of Medicine and Pharmacy
6 Senior Infectious Diseases Physician, INBI “Prof. Dr. Matei Balş”, Bucharest
Abstract
The Haemolytic-Uremic Syndrome (HUS) is the most frequent cause of renal failure in small children. Th is disease is often preceded by an episode of acute gastroenterocolitis caused by an enterohemorrhagic strain of Escherichia coli (0157:H7); the syndrome has been rarely associated with other bacterial or viral infections. HUS is more common in children younger than 4-5 years of age. Th e diagnosis is confi rmed by microangiopathic haemolytic anemia, thrombocytopenia, and acute renal failure. A more careful medical evaluation of the hematological and renal manifestations, together with early and repeated hemodialysis, give the best chance of recovery, even in the acute phase of the diseases.