ENDOSCOPIC MUCOSAL RESECTION OF A NEUROENDOCRINE DUODENAL TUMOR

June 1, 2015

Constantinescu G. 1, Ilie Mădălina 1, Baltac Alina 1, Plotogea Oana 1, Ciocirlan M. 2, Stănciulescu Luminiţa 1, Popa B. 1
1 Clinical Emergency Hospital Bucharest
2 Fundeni Clinical Institute Bucharest

Abstract

Duodenal neuroendocrine tumors (NETs) are rare neoplasms. In the US they have increased by 300% – 500% in the last 35 years. At the same time, their prognosis has improved. Today, most neuroendocrine tumors (NETs) of the duodenum are detected “incidentally” and therefore recognized at an early stage. Duodenal NETs which are well differentiated, not larger than 10 mm and limited to the mucosa/ submucosa can be endoscopically resected. We report a case of a 70 years old male patient admitted for iron deficiency anaemia. The colonoscopy showed a 3 mm polyp on the descending colon. The polypectomy was performed without incident. A duodenal mass was revealed at the upper endoscopy and the endosonography and endoscopic biopsy confirmed the diagnostic –duodenal neuroendocrine tumor. Because the tumor was limited to the submucosa and no lymphadenopathy or distant metastasis were seen on abdominal computed tomography (CT) endoscopic mucosal resection was performed without any incident.