Panduru M., Panduru NM., Ion DA.
2nd Department of Pathophysiology, „Carol Davila” University of Medicine and Pharmacy of Bucharest
Abstract
Atopic dermatitis is a disease whose incidence is continuously increasing. Administration of antibiotics in the first year of life is considered to be one of the factors which may influence the occurrence of the disease, but the studies are contradictory. This study aims to analyze the role of antibiotics in the occurrence of atopic dermatitis in a Romanian population group. Material and Method. We carried out a cross-sectional study on 1008 subjects regarding the administration of antibiotic in the first year of life and the occurrence of atopic dermatitis. All data were obtained by the distribution of questionnaires in schools and kindergartens. The analysis of data was made with MedCalc software, version 12.1.3.0. Results. Out of the patients diagnosed with atopic dermatitis, 47,4% received antibiotics in the first year of life, as compared to 39,5 % of those without atopic dermatitis. Antibiotherapy in the first year of life was not associated with atopic dermatitis in the simple logistic regression analysis (OR=1.38, P=0.13), nor yet after the adjustment for the other risk factors (OR=1.10, p=0.85). Conclusion. Antibiotherapy in the first year of life does not seem to be associated with a significant risk for developing atopic dermatitis.