A rare case of isolated oesophageal Crohn’s disease

December 1, 2015

Madalina I. 1, 2, Constantinescu G. 1, 2, Camelia D. 1, 2, Elena-Luminita S. 1, 2, Enache V. 1, 2, Macovei R. 1, 2, Popa B. 1, 2, Tincu R. 1, 2
1 UMF Carol Davila, Bucharest, Romania
2 Bucharest Emergency Hospital, Romania

Abstract

Crohn’s disease (CD) may affect any segment of the gastrointestinal tract. Although rare, its oesophageal manifestation may be seen as the first sign of this disease. We present the case of a 27 years old female who is admitted with heartburn and dysphagia for 4 years, being misdiagnosed as reflux esophagitis. Endoscopy performed in our unit pointed out erythema, segmental ulcers separated by normal mucosa, “cobble stone” aspect. The histological findings were ulcers and a chronic inflammatory mucosal infiltrate. The patient was unresponsive to PPI(Proton Pump Inhibitor), but a rapid improvement was seen after corticosteroid administration. Differential diagnosis and treatment opportunities are presented below.