MILIARY GENERALIZED TUBERCULOSIS WITH SUBACUTEEVOLUTION – CASE REPORT

September 1, 2010

Ruxandra Laza 1, A.Crişan 1, Emilia Nicoară 1
1 Department of Infectious Diseases, University of Medicine and Pharmacy “Dr. V.Babeş” Timişoara Romania

Abstract

Tuberculosis continues to be “the most lethal disease caused by a single pathogen”. The patient that we presented displayed a lot of factors involved in maintaining or re-emerging of tuberculosis infection as a disease (the presence of a low socio-economic level, lack of medical supervision and subsequently extension of a tuberculosis process). The initial clinical diagnosis was meningo-encephalitis syndrome, taken as a probably tuberculosis meningo-encephalitis based on CSF examination. It finally proved to be an extensive tuberculosis: meningeal, pulmonary, urogenital, endocrine. Death occurred on the tenth day of hospitalization and specific treatment, and it was preceded by the appearance of a purpuric syndrome, hepatic cytolysis and azotemia, interpreted as iatrogenic drug reaction.