Ramona Ionescu 1, D. Grigorescu 2, Gh. Pamfil 2
1 Hospital of Infectious Diseases, Mihai Viteazu 9, 500174 Braşov, Romania
2 Faculty of Medicine, Transilvania University, Braşov
Abstract
Antibiotic Control Programs were recommended by World Health Organization in order to minimize microbial resistance, provide the best therapy for patients, at the lowest costs for the healthcare institutions. We assessed the functionality of the Antibiotic Control Program in the Emergency County Hospital Braşov, over a period of two years (2004 – 2005). Method. This is a prospective descriptive study, based on the consults’ data, computed as daily entries into an excel table, by the infectious diseases specialist. Results. 670 infectious diseases consults were performed. 89% of the requests for therapy were for prescription of common antibiotics; approval of a restricted antibiotic represented 64% of the requests (p=0,0001). The direct communication between the physicians and the infectious diseases specialist was very good in 60% of the cases. This was significantly better with hematologists (82%) and internists (68%) than with intensivists (51%) or surgeons (51%); p<0,05. The adherence to the recommendations of the infectious diseases specialist was of 88%, 93% in the internal medicine department and 83% in the intensive care unit (p<0,05). The incidence of nosocomial infections was 26%. In 93 of the 124 patients (75%) with nosocomial infections, therapy with a restricted antibiotic was prescribed, but 17 of the patients died (14%). All of these patients benefited from therapy with at least one of the new antibiotics. Conclusions. The Antibiotherapy Control Program proved to be functioning successfully, in spite of the implementation difficulties in ICU and surgery. The program did in no way obstruct administration of ACP restricted antibiotics to patients with nosocomial infections.