ASPECTE CLINICE, MORFOLOGICE ȘI TERAPEUTICE ÎN INTOXICAȚIA ACUTĂ CU AMANITA PHALLOIDES

November 1, 2002

Cătălina Lionte *, S. Teleman **, Cristina Bologa *, L. Teodorescu ***, Elisabeta Manoilescu ***, O. Petriș *
* Cătălina Lionte – medic primar medicină internă, asistent universitar, Cristina Bologa – medic primar medicină internă, asistent universitar, O. Petriș – medic specialist medicină internă, asistent universitar – Clinica Medicală a Spitalului Clinic de Urgențe lași, U. M. F. Gr. T. Popa, lași
** S. Teleman – medic primar anatomie patologică, șef de lucrări – Disciplina Morfopatologie, U. M. F. Gr. T. Popa, lași
*** L. Teodorescu – medic specialist medicină legală, Elisabeta Manoilescu – medic primar medicină legală – Institutul de Medicină Legală Iași

Abstract

Most fatal intoxications by ingestion of toxic mushrooms are due to amatoxin-containing species, A. phalloides being the most representative. Clinical symptoms begin after a 6-12 hour period with a gastrointestinal disease phase, after which affected individuals feel better for a short period. Hepatic and renal lesions develop during this period, concomitantly with hypoglycemia, cardiac failure, seizures and coma, leadin.9 to death after 6-12 days of evolution. Ingestion of A. phalloides is responsible of 90% mortality from poisoning with amatoxin-containing mushrooms elsewhere. Survival is highly dependant on the amount of toxin ingested, its early diagnosis and treatment.